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Sequence Database

A comprehensive reference of verified amino acid sequences for all peptides in the AMP Peptide Research Database. Includes 1-letter and 3-letter codes, sequence length, N-terminal and C-terminal modifications, disulfide bridges, and post-translational modifications. Essential for synthesis verification, sequence alignment, and structural analysis.


🔬 Sequence Notation Guide

Notation Example Meaning
1-letter code MEHFPGP Standard IUPAC single-letter amino acid codes
3-letter code Met-Glu-His-Phe-Pro-Gly-Pro Standard IUPAC three-letter codes with hyphens
N-terminal H- or Ac- Free amine or acetylated N-terminus
C-terminal -OH or -NH₂ Free acid or amidated C-terminus
Pal- Palmitoyl group C16 fatty acid modification
Ac- Acetyl group N-terminal acetylation
Modified residues (D-Ala), (Hcy) Non-standard or D-amino acids
Disulfide bridge Cys¹–Cys⁶ Disulfide bond between specified cysteines

1. Neurocognitive Peptides

Semax

Property Value
Sequence (1-letter) MEHFPGP
Sequence (3-letter) Met-Glu-His-Phe-Pro-Gly-Pro
Length 7 amino acids
N-terminus Free (H-Met-)
C-terminus Free acid (-Pro-OH)
Modifications None
Disulfide Bridges None
Molecular Formula C₃₇H₅₃N₉O₁₀S
MW (Average) 706.83 Da
Class Synthetic ACTH(4–10) analogue

Selank

Property Value
Sequence (1-letter) TKPRPGP
Sequence (3-letter) Thr-Lys-Pro-Arg-Pro-Gly-Pro
Length 7 amino acids
N-terminus Free (H-Thr-)
C-terminus Free acid (-Pro-OH)
Modifications None
Disulfide Bridges None
Molecular Formula C₃₃H₅₇N₁₁O₉
MW (Average) 756.89 Da
Class Synthetic tuftsin analogue

Noopept

Property Value
Chemical Name N-Phenylacetyl-L-Prolylglycine Ethyl Ester
IUPAC Name Ethyl 2-[(2S)-1-(2-phenylacetyl)pyrrolidine-2-amido]acetate
Length Non-peptide (dipeptide analogue)
N-terminus Phenylacetyl cap
C-terminus Ethyl ester
Molecular Formula C₁₇H₂₂N₂O₄
MW (Average) 342.39 Da
Class Cycloprolylglycine analogue

Cerebrolysin

Property Value
Composition Porcine brain-derived peptide hydrolysate
MW Range 120–10,000 Da
Peptide Fraction ~80% low-molecular-weight peptides, ~20% free amino acids
Major Peptide Motifs BDNF-like, GDNF-like, CNTF-like, NT-3-like, IGF-1-like fragments
Free Amino Acids Glu, Asp, Gly, Ala, Arg, Lys, Leu, Ser, Thr, Val (significant levels)
Sequence Not applicable (complex mixture of > 100 peptide species)
Class Multi-modal neurotrophic peptide cocktail

2. Sleep & Pineal Peptides

Epitalon

Property Value
Sequence (1-letter) AEDG
Sequence (3-letter) Ala-Glu-Asp-Gly
Length 4 amino acids
N-terminus Free (H-Ala-)
C-terminus Free acid (-Gly-OH)
Modifications None
Disulfide Bridges None
Molecular Formula C₁₄H₂₂N₄O₉
MW (Average) 375.35 Da
Class Synthetic pineal tetrapeptide

Pinealon

Property Value
Sequence (1-letter) EDR
Sequence (3-letter) Glu-Asp-Arg
Length 3 amino acids
N-terminus Free (H-Glu-)
C-terminus Free acid (-Arg-OH)
Modifications None
Disulfide Bridges None
Molecular Formula C₁₅H₂₆N₆O₈
MW (Average) 431.41 Da
Class Synthetic pineal tripeptide

3. Growth & Signaling Peptides

Ipamorelin

Property Value
Sequence (1-letter) Aib-His-(D-Nal)-Ala-Trp-(D-Phe)-Lys-NH₂
Sequence (3-letter) Aib-His-(D-2-Nal)-Ala-Trp-(D-Phe)-Lys-NH₂
Length 5 modified residues
N-terminus Free (H-Aib-)
C-terminus Amidated (-Lys-NH₂)
Modifications Aib (α-aminoisobutyric acid), D-2-Nal (D-2-naphthylalanine), D-Phe
Disulfide Bridges None
Molecular Formula C₃₈H₄₉N₉O₅
MW (Average) 711.86 Da
Class GHSR agonist (pentapeptide)

GHRP-2 (Pralmorelin)

Property Value
Sequence (1-letter) (D-Ala)-(D-β-Nal)-Ala-Trp-(D-Phe)-Lys-NH₂
Sequence (3-letter) D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH₂
Length 6 modified residues
N-terminus Free (H-D-Ala-)
C-terminus Amidated (-Lys-NH₂)
Modifications D-Ala, D-β-Nal (D-β-naphthylalanine), D-Phe
Disulfide Bridges None
Molecular Formula C₄₅H₅₄N₁₂O₆
MW (Average) 786.93 Da
Class GHSR agonist (hexapeptide)

GHRP-6

Property Value
Sequence (1-letter) His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH₂
Sequence (3-letter) His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Length 6 modified residues
N-terminus Free (H-His-)
C-terminus Amidated (-Lys-NH₂)
Modifications D-Trp, D-Phe
Disulfide Bridges None
Molecular Formula C₄₆H₅₆N₁₂O₆
MW (Average) 801.00 Da
Class GHSR agonist (hexapeptide)

CJC-1295

Property Value
Sequence (1-letter) YADAIFTNSYRKVLGQLSARKLLQDIMSRQ
Sequence (3-letter) Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln
Length 30 amino acids
N-terminus Free (H-Tyr-)
C-terminus Amidated (-Gln-NH₂)
Modifications C-terminal amidation; commonly with DAC (Drug Affinity Complex) at Lys
Disulfide Bridges None
Molecular Formula C₁₅₂H₂₅₂N₄₄O₄₂
MW (Average) 3315.74 Da
Class GHRH analogue with DAC

Sermorelin

Property Value
Sequence (1-letter) YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH₂
Sequence (3-letter) Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂
Length 29 amino acids
N-terminus Free (H-Tyr-)
C-terminus Amidated (-Arg-NH₂)
Modifications C-terminal amidation
Disulfide Bridges None
Molecular Formula C₁₅₃H₂₅₃N₄₅O₄₂S
MW (Average) 3357.86 Da
Class GHRH fragment (1–29)

4. GLP-1 Receptor Agonists

Tirzepatide

Property Value
Sequence (1-letter) YXGEGTFTSDYSIVLDKIAQKAFVQWLIAGGPSSGAPPPS-NH₂ (X = Aib)
Length 39 amino acids (modified)
N-terminus Free (H-Tyr-)
C-terminus Amidated
Key Modifications Aib at position 2; C20 diacid fatty diacid chain (γGlu-PEG₃-C20) at Lys²⁰
Class GIP/GLP-1 dual receptor agonist

Retatrutide

Property Value
Sequence Related to tirzepatide backbone with triple receptor activity (GIP/GLP-1/glucagon)
Length 39 amino acids (modified)
C-terminus Amidated
Key Modifications Fatty acid acylation at Lys residue
Class GIP/GLP-1/glucagon triple receptor agonist

Semaglutide

Property Value
Sequence Extended GLP-1 (7–37) analogue with modifications
Length 31 amino acids
N-terminus Modified (protection against DPP-4)
C-terminus Free acid (-OH)
Key Modifications Aib at Aib⁸, Lys²⁶ with C18 diacid chain via γGlu spacer
Class GLP-1 receptor agonist

5. Cosmetic & Topical Peptides

GHK-Cu (Copper Tripeptide-1)

Property Value
Sequence (1-letter) GHK
Sequence (3-letter) Gly-His-Lys
Length 3 amino acids
N-terminus Free (H-Gly-)
C-terminus Free acid (-Lys-OH)
Metal Binding Cu²⁺ coordinated by His imidazole and Gly/Lys amino groups
Class Copper-binding tripeptide

Matrixyl (Palmitoyl Pentapeptide-4)

Property Value
Sequence (1-letter) Pal-KTTKS
Sequence (3-letter) Pal-Lys-Thr-Thr-Lys-Ser
Length 5 amino acids
N-terminus Palmitoylated (C16)
C-terminus Free acid (-Ser-OH)
Modifications N-terminal palmitoylation
Class Collagen-stimulating pentapeptide

Argireline (Acetyl Hexapeptide-8)

Property Value
Sequence (1-letter) Ac-EEMQRR-NH₂
Sequence (3-letter) Ac-Glu-Glu-Met-Gln-Arg-Arg-NH₂
Length 6 amino acids
N-terminus Acetylated (Ac-)
C-terminus Amidated (-NH₂)
Class SNAP-25 inhibitor (wrinkle relaxant)

SNAP-8 (Acetyl Octapeptide-3)

Property Value
Sequence (1-letter) Ac-EEMQRR-NH₂ (extended variant)
Length 8 amino acids
N-terminus Acetylated (Ac-)
C-terminus Amidated (-NH₂)
Class SNAP-25 inhibitor (enhanced activity)

6. Tissue Repair & Regenerative Peptides

BPC-157 (Body Protection Compound-157)

Property Value
Sequence (1-letter) GEPPPGKPADDAGLV
Sequence (3-letter) Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Length 15 amino acids
N-terminus Free (H-Gly-)
C-terminus Free acid (-Val-OH)
Modifications None
Disulfide Bridges None
Partial Sequence Derived from human gastric juice protein BPC
Class Stable gastric pentadecapeptide

TB-500 (Thymosin Beta-4 Synthetic Fragment)

Property Value
Sequence (1-letter) SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Length 43 amino acids
N-terminus Free (H-Ser-) or Acetylated
C-terminus Free acid
Modifications Variable acetylation
Disulfide Bridges None
Class G-actin sequestering protein fragment

7. Mitochondrial & Metabolic Peptides

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)

Property Value
Sequence (1-letter) MRWQEMGYIFYPRKLR
Sequence (3-letter) Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Length 16 amino acids
N-terminus Free (H-Met-)
C-terminus Free acid (-Arg-OH)
Class Mitochondrial-derived peptide

SS-31 (Elamipretide)

Property Value
Sequence (1-letter) (D-Arg)-(2',6'-Dmt)-Lys-Phe-NH₂
Sequence (3-letter) D-Arg-2',6'-dimethyltyrosine-Lys-Phe-NH₂
Length 4 modified amino acids
N-terminus Free (H-D-Arg-)
C-terminus Amidated (-NH₂)
Modifications D-Arg, 2',6'-dimethyltyrosine (Dmt)
Class Mitochondrial-targeted cardiolipin stabilizer

Humanin

Property Value
Sequence (1-letter) MAPRGFSCLLLLTSEIDLPVKRRA
Sequence (3-letter) Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
Length 24 amino acids
N-terminus Free (H-Met-)
C-terminus Free acid (-Ala-OH)
Disulfide Bridges Cys⁸ involved in potential dimerization
Class Mitochondrial-derived cytoprotective peptide

AOD-9604

Property Value
Sequence (1-letter) LRRIRHMAEHERRL
Sequence (3-letter) Leu-Arg-Arg-Ile-Arg-His-Met-Ala-Glu-His-Glu-Arg-Arg-Leu
Length 15 amino acids
N-terminus Free (H-Leu-)
C-terminus Free acid (-Leu-OH)
Modifications Derived from hGH 177–191 fragment
Class Human growth hormone fragment (lipolytic)

📊 Sequence Length Summary

Peptide Length 1-Letter Sequence Category
Pinealon 3 EDR Sleep
Epitalon 4 AEDG Sleep
GHK-Cu 3 GHK Cosmetic
SS-31 4 (modified) (D-Arg)-Dmt-Lys-Phe-NH₂ Mito
Matrixyl 5 Pal-KTTKS Cosmetic
Argireline 6 Ac-EEMQRR-NH₂ Cosmetic
GHRP-2 6 (modified) (D-Ala)-(D-β-Nal)-Ala-Trp-(D-Phe)-Lys-NH₂ Growth
GHRP-6 6 (modified) His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH₂ Growth
Semax 7 MEHFPGP Neuro
Selank 7 TKPRPGP Neuro
SNAP-8 8 (modified) Ac-EEMQRR (extended) -NH₂ Cosmetic
BPC-157 15 GEPPPGKPADDAGLV Tissue Repair
AOD-9604 15 LRRIRHMAEHERRL Mito
MOTS-c 16 MRWQEMGYIFYPRKLR Mito
Humanin 24 MAPRGFSCLLLLTSEIDLPVKRRA Mito
Sermorelin 29 YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH₂ Growth
CJC-1295 30 YADAIFTNSYRKVLGQLSARKLLQDIMSRQ Growth
Semaglutide 31 (modified) Extended GLP-1 analogue GLP-1
Tirzepatide 39 (modified) YXGEGTFTSDYSIVLDKIAQKAFVQWLIAGGPSSGAPPPS-NH₂ GLP-1
TB-500 43 SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES Tissue Repair

Browse peptide sequences at AMP Peptide